Humans in A Dish: Gene Editing for Down Syndrome Therapeutics

Humans in A Dish: Gene Editing for Down Syndrome Therapeutics

13 September 2019

11:00AM - 11:45AM


Multi-Purpose Hall 1, Innovis

Through editing stem cells with defective mutations found in the human genetic code, potential hard-to-treat diseases could now potentially be reverted. 

Join Dr Aparna Venkatesh as she gives us a glimpse of the exciting world of stem cell research which has vast potential for understanding Down Syndrome and other genetic diseases. Dr Venkatesh employs Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) in human disease modelling and looks to mitigate health complications like congenital heart defects in Down Syndrome and finding specific drug targets for future treatment.



Dr Aparna Venkatesh

Dr Aparna Venkatesh

Senior Research Fellow
Molecular Engineering Lab (MEL), A*STAR

Dr Venkatesh received a PhD in Immunology from the University of Milano-Bicocca, Italy. Her PhD work focused on similarities and differences of innate immune responses, and in particular, dendritic cell activation. As a Senior Research Fellow at the Molecular Engineering Laboratory in A*STAR, she heads a stem cell human disease modelling project to develop in-vitro cellular models for neurological and genetic disorders. She has also been actively involved in the Stem Cell Society of Singapore and was the chairperson of their biennial Young Investigator’s Symposium.